This manuscript contains approximately 45 medical receipts on 88 pages (about half are blank). Includes remedies for piles, wens, warts, burns, fever, croup, rheumatism, and gravel, among others. Some remedies are accompanied by prayers. The manuscript is in predominately one hand, possibly that of Susanna Weinbrech Hoffmann (1742-1803) or Lydia Henkel Hoffman. The only confirmed hand in the book is that of William Hoffman (1809-1886), Lydia's son, on the last page of the book.